What would you think if food no longer smelled the way it used to, or the scent of flowers seemed to fade? Most of us would brush it off as just getting older. But recent research suggests this small change may deserve a second look.
In April 2026, a research team at the Daegu Gyeongbuk Institute of Science and Technology (DGIST) in Korea published a study in Alzheimer's & Dementia. Analyzing brain tissue from donors at different stages of the disease, the team confirmed that the toxic proteins behind Alzheimer's — amyloid beta and tau — build up first in the olfactory bulb and olfactory cortex, the parts of the brain that detect and identify smells, before spreading elsewhere. It was the first study to explain, at the cellular level, why the sense of smell is damaged earliest.
In other words, trouble smelling may appear years before memory problems do. Long before memory begins to slip, the nose may be sending an early signal.
A team led by Dr. Davangere Devanand at Columbia University reached a similar conclusion. Following 647 participants in the Mayo Clinic Study of Aging for an average of eight years, they found that a simple test — identifying 12 common smells — combined with a brief cognitive exam predicted cognitive decline and progression to dementia about as well as costly PET brain scans. An important clue, it turns out, can come from something as simple as naming a smell.
Of course, losing your sense of smell does not mean you have dementia. Far more common causes include colds, sinus problems, after-effects of COVID-19, smoking, and ordinary aging. Smell loss alone can never diagnose the disease.
Still, if your sense of smell has changed and the change lasts, it is worth mentioning to an ear, nose, and throat doctor or a neurologist. Finding out whether the cause lies in the nose or somewhere else can bring real peace of mind.
No elaborate test is needed to begin. At the dinner table, or on a walk past blooming flowers, quietly check whether your senses feel the same as before. Noticing the small signals your body sends may be the first step to protecting your health.
References: Moon et al., Alzheimer's & Dementia, April 2026 / Devanand et al., Alzheimer's & Dementia, October 2024
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The items below relate to everyday smell care. Smell training — briefly sniffing strong, familiar scents each day — is a simple exercise often suggested for people whose sense of smell has faded, and a saline rinse can help when congestion or sinus trouble is the cause. Please note: no supplement or product treats smell loss or prevents dementia. If your sense of smell has changed and the change lasts, please see an ear, nose, and throat doctor or a neurologist, as this article describes.
Note: These are product categories, not specific product recommendations. They cannot restore the sense of smell or prevent dementia.
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